Synthesis of New Triazolyl-N,N-Dialkyldithiocarbamates as Antifungal Agents

N,N-Dialkylditihiocarbamate derivatives have been well known as broad-range fungicides. In this study, the triazole derivatives of ten new N,N-disubstituted dithiocarbamates (3a-j) were synthesized and their structures were identified by spectral and elemental analysis. Results of the antifungal act...

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Veröffentlicht in:Archives of pharmacal research 2005, 28(11), , pp.1213-1218
Hauptverfasser: Ozkirimli Sumru, Apak T. Idil, Kiraz Muammer, Yegenoglu Yildiz
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Sprache:kor
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Zusammenfassung:N,N-Dialkylditihiocarbamate derivatives have been well known as broad-range fungicides. In this study, the triazole derivatives of ten new N,N-disubstituted dithiocarbamates (3a-j) were synthesized and their structures were identified by spectral and elemental analysis. Results of the antifungal activity studies showed that some of the compounds tested were active against M. canis, M. gypseum, and T rubrum at the concentration of 12.5 $\mu$g/mL when c1otrimazol was used as a standard.
ISSN:0253-6269
1976-3786