A new monoterpene glycoside and antibacterial monoterpene glycosides from Paeonia suffruticosa

Antibacterial activity-guided fractionation of the CHCI3-MeOH (1:1) extract of Paeonia suffruticosa root bark furnished three monoterpene glycosides, 6-O-vanillyoxypaeoniflorin (1), mudanpioside-H (2), and galloyl-oxypaeoniflorin (3). Of the isolated compounds, compound 1 is a new compound. All isol...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Archives of pharmacal research 2006, 29(10), , pp.815-820
Hauptverfasser:	An, Ren-Bo, Kim, Hyun-Chul, Lee, Sung-Hee, Jeong, Gil-Saeng, Sohn, Dong-Hwan, Park, Hyun, Kwon, Dong-Yeul, Lee, John Hwa, Kim, Youn-Chul
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - isolation & purification Anti-Bacterial Agents - pharmacology Escherichia coli - classification Escherichia coli - drug effects Escherichia coli - growth & development Gallic Acid - analogs & derivatives Gallic Acid - chemistry Gallic Acid - isolation & purification Gallic Acid - pharmacology Glucosides - chemistry Glucosides - isolation & purification Glucosides - pharmacology Glycosides - chemistry Glycosides - isolation & purification Glycosides - pharmacology Methicillin Resistance - drug effects Methicillin Resistance - genetics Microbial Sensitivity Tests - methods Molecular Structure Monoterpenes - chemistry Monoterpenes - isolation & purification Monoterpenes - pharmacology Paeonia - chemistry Plant Roots - chemistry Salmonella enteritidis - classification Salmonella enteritidis - drug effects Salmonella enteritidis - growth & development Shigella flexneri - drug effects Shigella flexneri - growth & development Staphylococcus aureus - drug effects Staphylococcus aureus - genetics Staphylococcus aureus - growth & development Triterpenes - chemistry Triterpenes - isolation & purification Triterpenes - pharmacology Vibrio cholerae - drug effects Vibrio cholerae - growth & development 약학
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Antibacterial activity-guided fractionation of the CHCI3-MeOH (1:1) extract of Paeonia suffruticosa root bark furnished three monoterpene glycosides, 6-O-vanillyoxypaeoniflorin (1), mudanpioside-H (2), and galloyl-oxypaeoniflorin (3). Of the isolated compounds, compound 1 is a new compound. All isolated compounds showed broad, but moderate, antibacterial activity with minimum inhibitory concentration (MIC) values in the range of 100 to 500 microg/mL against eighteen pathogenic microorganisms of concern for public health or zoonosis.
ISSN:	0253-6269 1976-3786
DOI:	10.1007/BF02973899