Ethosomes, binary ethosomes and transfersomes of terbinafine hydrochloride: A comparative study

The aim of this study was to compare the skin permeation of ethosomes, binary ethosomes and transfersomes of Terbinafine Hydrochloride (TH) under non-occlusive conditions. These lipid vesicles were prepared and characterized for shape, size, zeta-potential and entrapment efficiency. Franz diffusion...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Archives of pharmacal research 2012, 35(1), , pp.109-117
Hauptverfasser:	Zhang, Jian-Ping, Wei, Yu-Hui, Zhou, Yan, Li, Yu-Qing, Wu, Xin-An
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Cutaneous Animals Drug Carriers - administration & dosage Drug Carriers - pharmacokinetics Liposomes - administration & dosage Liposomes - pharmacokinetics Male Medicine Mice Naphthalenes - administration & dosage Naphthalenes - pharmacokinetics Pharmacology/Toxicology Pharmacy Research Article Rhodamines - administration & dosage Rhodamines - pharmacokinetics Skin Absorption 약학
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The aim of this study was to compare the skin permeation of ethosomes, binary ethosomes and transfersomes of Terbinafine Hydrochloride (TH) under non-occlusive conditions. These lipid vesicles were prepared and characterized for shape, size, zeta-potential and entrapment efficiency. Franz diffusion cells and confocal laser scanning microscopy (CLSM) were used for the percutaneous absorption studies. The quantity of drug in the skin from ethosomes, binary ethosomes (the weight ratio of ethanol to propylene glycol 7:3, ethanol-PG = 7:3, w/w), and transfersomes was 1.26, 1.51 ( p
ISSN:	0253-6269 1976-3786
DOI:	10.1007/s12272-012-0112-0