Dual Action 기능을 가지도록 설계한 항경련성 전구약물의 합성과 항경련 활성

Dual Action 기능을 가지도록 설계한 항경련성 전구약물의 합성과 항경련 활성

This study aimed to synthesize new anticonvulsive agents as potential dual acting prodrugs. For the synthesis of ester or amide prodrug types, p-hydroxybenzaldehyde or valproic acid was coupled with clinically usable anticonvulsants or GABAmimetics with use of DCC/DMAP coupling methods. Also their a...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Yaghag-hoi-ji 2004, 48(3), , pp.182-188
Hauptverfasser: 김은경(Eun-kyung Kim), 최병기(Byong Ki Choi), 김종걸(Jong Geol Kim), 이정희(Jeong Hee Lee), 최종원(Jong Won Choi), 이응석(Eung-Seok Lee)
Format: Artikel
Sprache:kor
Schlagworte:
약학
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:This study aimed to synthesize new anticonvulsive agents as potential dual acting prodrugs. For the synthesis of ester or amide prodrug types, p-hydroxybenzaldehyde or valproic acid was coupled with clinically usable anticonvulsants or GABAmimetics with use of DCC/DMAP coupling methods. Also their anticonvulsive activities were evaluated.
ISSN:0377-9556
2383-9457