3-메톡시-6-알릴치오피리다진의 사람 췌장암 세포 사멸작용

3-메톡시-6-알릴치오피리다진의 사람 췌장암 세포 사멸작용

In this study we investigated the effect of 3-methoxy-6-allylthiopyridazine on cell growth in BxPC3 and PANC1 human pancreatic cancer cells. The treatment with 3-methoxy-6-allylthiopyridazine for 48h decreased cell viability and induced apoptotic cell death in a dose-dependent manner, assessed by us...

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Veröffentlicht in:Yaghag-hoi-ji 2005, 49(4), , pp.335-339
Hauptverfasser: 강영신(Young Shin Kang), 서연원(Yeon Won Suh), 권순경(Soon Kyung Kwon), 정춘식(Choon Sik Jeong), 이용수(Yong Soo Lee)
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Sprache:kor
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약학
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Zusammenfassung:In this study we investigated the effect of 3-methoxy-6-allylthiopyridazine on cell growth in BxPC3 and PANC1 human pancreatic cancer cells. The treatment with 3-methoxy-6-allylthiopyridazine for 48h decreased cell viability and induced apoptotic cell death in a dose-dependent manner, assessed by using the MTT assay and the flow cytometry, respectively. These results suggest that 3-methoxy-6-allylthiopyridazine may be a good candidate for the therapeutic management of human pancreatic cancers.
ISSN:0377-9556
2383-9457