DNA Budding of Primo Microcells

DNAs proliferate principally by doubling. However, they are more versatile than this simple copying. They can be transformed by splicing and recombination. They can even grow by budding as observed by Bong-Han Kim [1] in the early 1960s. A similar observation was reported in the case of human sarcoma cancer cells [2]. The primo microcell (PMC) is a spherical body whose size is 1–2 μm, contains one or few chromosomes, and circulates in the primo vascular system. Kim [1] claimed that the DNA in the PMC buds to form a daughter PMC. KCI Citation Count: 0