Blood pressure control in diabetic kidney disease: a post-hoc analysis of the FANTASTIC trial

The target blood pressure (BP) value is unclear for diabetic kidney disease (DKD). Therefore, we aimed to evaluate the effect of strict BP control or 'on treatment' BP on clinical outcomes in patients with DKD. A post-hoc analysis of the prespecified secondary outcomes of the FimAsartaN pr...

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Veröffentlicht in:	Clinical hypertension 2024, 30(0), , pp.20-20
Hauptverfasser:	Park, Cheol Ho, Hong, Soon Jun, Kim, Sung Gyun, Shin, Seok Joon, Kim, Dong Ki, Lee, Jung Pyo, Han, Sang Youb, Lee, Sangho, Won, Jong Chul, Kang, Young Sun, Park, Jongha, Han, Byoung-Geun, Na, Ki-Ryang, Hur, Kyu Yeon, Kim, Yong-Jin, Park, Sungha, Yoo, Tae-Hyun
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Antihypertensive drugs Blood pressure Cardiovascular diseases Cardiovascular outcome Care and treatment Chronic kidney failure Clinical outcomes Creatinine Diabetes Diabetic kidney disease Diabetic nephropathies Diabetics Diagnosis Dosage and administration Electrolytes Kidney diseases Kidney outcome Orthostatic hypotension Prevention Regulation Risk factors Type 2 diabetes 내과학
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Zusammenfassung:	The target blood pressure (BP) value is unclear for diabetic kidney disease (DKD). Therefore, we aimed to evaluate the effect of strict BP control or 'on treatment' BP on clinical outcomes in patients with DKD. A post-hoc analysis of the prespecified secondary outcomes of the FimAsartaN proTeinuriA SusTaIned reduCtion in comparison with losartan in diabetic chronic kidney disease (FANTASTIC) trial, a randomized multicenter double-blind phase III trial. Eligible patients were aged ≥ 19 years with DKD. We assigned 341 participants with DKD to BP control strategy (standard-systolic BP [SBP]
ISSN:	2056-5909 1342-2154 2635-6325 2056-5909
DOI:	10.1186/s40885-024-00280-x