Efficacy and Safety of Metformin and Atorvastatin Combination Therapy vs. Monotherapy with Either Drug in Type 2 Diabetes Mellitus and Dyslipidemia Patients (ATOMIC): Double-Blinded Randomized Controlled Trial

It is well known that a large number of patients with diabetes also have dyslipidemia, which significantly increases the risk of cardiovascular disease (CVD). This study aimed to evaluate the efficacy and safety of combination drugs consisting of metformin and atorvastatin, widely used as therapeuti...

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Veröffentlicht in:Diabetes & metabolism journal 2024, 48(4), 204, pp.730-739
Hauptverfasser: Lee, Jie-Eun, Yu, Seung Hee, Kim, Sung Rae, Ahn, Kyu Jeung, Song, Kee-Ho, Lee, In-Kyu, Shon, Ho-Sang, Kim, In Joo, Lim, Soo, Kim, Doo-Man, Chung, Choon Hee, Lee, Won-Young, Lee, Soon Hee, Kim, Dong Joon, Cho, Sung-Rae, Jung, Chang Hee, Jeon, Hyun Jeong, Lee, Seung-Hwan, Park, Keun-Young, Rhee, Sang Youl, Kim, Sin Gon, Park, Seok O, Kim, Dae Jung, Kim, Byung Joon, Lee, Sang Ah, Kim, Yong-Hyun, Kim, Kyung-Soo, Seo, Ji A, Nam-Goong, Il Seong, Lee, Chang Won, Kim, Duk Kyu, Kim, Sang Wook, Cho, Chung Gu, Kim, Jung Han, Kim, Yeo-Joo, Yoo, Jae-Myung, Min, Kyung Wan, Lee, Moon-Kyu
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Sprache:eng
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Zusammenfassung:It is well known that a large number of patients with diabetes also have dyslipidemia, which significantly increases the risk of cardiovascular disease (CVD). This study aimed to evaluate the efficacy and safety of combination drugs consisting of metformin and atorvastatin, widely used as therapeutic agents for diabetes and dyslipidemia. This randomized, double-blind, placebo-controlled, parallel-group and phase III multicenter study included adults with glycosylated hemoglobin (HbA1c) levels >7.0% and 100 and
ISSN:2233-6079
2233-6087
2233-6087
DOI:10.4093/dmj.2023.0077