말단골용해를 동반한 일차성 비후성 골관절증 1예

일차성 비후성 골관절증은 원인이 될만한 기저 질환이 없이 곤봉지, 피부와 두피가 두꺼워지는 연조직의 변화와 골막 반응을 특징으로 하는 드문 유전 질환으로, 저자들은 말단골용해 소견을 동반한 일차성 비후성 골관절증을 진단하고 약물치료를 시행하였던 증례를 경험하여 이를 보고하는 바이다. Primary hypertrophic osteoarthropathy or pachydermoperiostosis is a rare hereditary disorder characterized by digital clubbing, pachydermia and periostosis. Its precise incidence and prevalence is still unknown due to the lack of controlled data. It occurs without any underlying causes and usually has a chronic course. Life expectancy may be of normal standards, but many patients develop multiple functional and cosmetic complications. So, it is important to diagnose this disease at an early stage and to treat the symptomat for the quality of life. We report a case of primary hypertrophic osteoarthropathy in a 68-year-old male with clinical features such as digital clubbing and pachydermia, radiographic findings of acroosteolysis and periosteal new bone formation.