정천탕의 알러지에 대한 실험적 연구
목적 : 정천탕(定喘湯, JCT)이 IgE/mast cell로 유도되는 천식(喘息)등의 알러지성 질환에 대한 효과를 실험적으로 검증하고자 하였다. This report describes an inhibitory effect of Jungchuntang(JCT) on immediate hypersensitivity through IgE/mast cell/mediator pathaway. JCT is an Oriental herbal medication, which has been used for the treatment of alle...
Gespeichert in:
| Veröffentlicht in: | 대한한의학회지, 24(3) 2003, 24(3), , pp.495-501 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | kor |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| Zusammenfassung: | 목적 : 정천탕(定喘湯, JCT)이 IgE/mast cell로 유도되는 천식(喘息)등의 알러지성 질환에 대한 효과를 실험적으로 검증하고자 하였다. This report describes an inhibitory effect of Jungchuntang(JCT) on immediate hypersensitivity through IgE/mast cell/mediator pathaway. JCT is an Oriental herbal medication, which has been used for the treatment of allergic patients with espatially asthma in Korea. JCT significantly inhibited the IgE production in mice and IL-4 + anti CD40-mediated IgE production in vitro. JCT promoted IFN-expression but inhibited IL-4 and IL-6 mRNA expression. JCT dose-dependently inhibited the compound 48/80-induced histamine release from mast cell line, IC-2 cell. Thease results indicated that JCT has treatmentary effect on atopic disorder, such as asthma. KCI Citation Count: 1 |
|---|---|
| ISSN: | 1010-0695 2288-3339 |