加味逍遙散이 가임기 난소기능저하 불임여성의 난소기능개선에 미치는 영향에 관한 후향적 연구

Objectives:This study was performed to elicit the effectiveness of a herbal formula, Kamisoyo-san (Jiaweixiaoyao- san) on enhancing ovarian function in infertile woman with ovarian dysfunction. Methods:28 patients who initially visited between November 2006 and February 2009 and were administered Kamisoyo-san until May 2009 were retrospectively evaluated for their ovarian function by means of basal FSH (b-FSH), menstrual cycle, body mass index (BMI), and body fat ratio. To identify the major factor of improving ovarian function, 28 patients were classified into two groups by criteria of patent factors, such as pre-administration b-FSH, patient age, and treatment duration, respectively. Two groups were compared in terms of pregnancy percentage, b-FSH, menstrual cycle, BMI, and body fat ratio. Results:Post-administration b-FSH significantly decreased in comparison with pre-administration (p=0.004). The higher group (b-FSH ≥ 25mIU/mL) in pre-administration b-FSH was more effective in decrease of post-administration b-FSH than the lower one (10mIU/mL < b-FSH < 25mIU/mL). Conclusion:Kamisoyo-san may have a therapeutic effect on the infertility of child bearing period woman with ovarian dysfunction. Objectives:This study was performed to elicit the effectiveness of a herbal formula, Kamisoyo-san (Jiaweixiaoyao- san) on enhancing ovarian function in infertile woman with ovarian dysfunction. Methods:28 patients who initially visited between November 2006 and February 2009 and were administered Kamisoyo-san until May 2009 were retrospectively evaluated for their ovarian function by means of basal FSH (b-FSH), menstrual cycle, body mass index (BMI), and body fat ratio. To identify the major factor of improving ovarian function, 28 patients were classified into two groups by criteria of patent factors, such as pre-administration b-FSH, patient age, and treatment duration, respectively. Two groups were compared in terms of pregnancy percentage, b-FSH, menstrual cycle, BMI, and body fat ratio. Results:Post-administration b-FSH significantly decreased in comparison with pre-administration (p=0.004). The higher group (b-FSH ≥ 25mIU/mL) in pre-administration b-FSH was more effective in decrease of post-administration b-FSH than the lower one (10mIU/mL < b-FSH < 25mIU/mL). Conclusion:Kamisoyo-san may have a therapeutic effect on the infertility of child bearing period woman with ovarian dysfunction. KCI Citation Count: 5