Low serum total testosterone level as a predictor of upgrading in low-risk prostate cancer patients after radical prostatectomy: A systematic review and meta-analysis

To investigated the association between serum total testosterone and Gleason score upgrading of low-risk prostate cancer after radical prostatectomy (RP). Medline, Web of Science, Embase, and Cochrane Library databases were searched to identify eligible studies published before October 2021. Multiva...

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Veröffentlicht in:Investigative and clinical urology 2022, 63(4), , pp.407-414
Hauptverfasser: Gan, Shu, Liu, Jian, Chen, Zhiqiang, Xiang, Songtao, Gu, Chiming, Li, Siyi, Wang, Shusheng
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Sprache:eng
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Zusammenfassung:To investigated the association between serum total testosterone and Gleason score upgrading of low-risk prostate cancer after radical prostatectomy (RP). Medline, Web of Science, Embase, and Cochrane Library databases were searched to identify eligible studies published before October 2021. Multivariate adjusted odds ratios (ORs) and associated 95% confidence intervals (CIs) were calculated using random or fixed effects models. Five studies comprising 1,203 low-risk prostate cancer patients were included. The results showed that low serum total testosterone (
ISSN:2466-0493
2466-054X
DOI:10.4111/icu.20210459