Growth of 2D-layered double hydroxide nanorods heterojunction with 2D tungsten carbide nanocomposite: Improving the electrochemical sensing of norfloxacin

[Display omitted] •NiCo-LDH is prepared through facile hydrothermal process.•NiCo-LDH ultrasonically treated with tungsten carbide (WC) forming a composite.•The WC (2D) integrated with NiCo-LDH (2D) provides excellent active sites for norfloxacin (NRF) detection.•The LOD was about DPV = 0.005 µM and i-t = 0.002 µM, with a sensitivity of DPV = 6.53 and i-t = 40.81 μA/μM/cm2.•The real sample sensing with the WC@NiCo-LDH electrode exhibited good recovery results of NRF. The potential impact of antibiotics in water environments affects aquatic organisms, microbial community structure, and resistance genes. In this work, we report the hydrothermal synthesis of two-dimensional (2D) tungsten carbide (WC) nanoparticles on CO32- anion intercalated three-dimensional (3D) self-assembled nickel–cobalt layered double hydroxide (NiCo-LDH) nanorods, for the electrochemical determination of norfloxacin (NRF). The synergistic impact between the dual active components of the prepared electrode offered increased active surface area, high electrical conductivity, and prompt mass and ion diffusion, resulting in improved electrochemical performance for NRF monitoring. In ideal conditions, WC@NiCo-LDH modified electrode exhibited enhanced electrochemical characteristics, wide linear response (DPV = 0.02–83.4 µM and in i-t = 0.002–346 µM), and lowdetection limit (LOD) (DPV = 0.005 µM and i-t = 0.002 µM). Furthermore, good reproducibility, virtuous operational and cycle stabilities, were obtained. The practical applications in real-world samples with acceptable recovery ranges were verified the interference-free sensing of NRF.