Biosynthesis of Mycophenolic Acid

Biosynthesis of Mycophenolic Acid

Comparative incorporation experiments with (1′- 14 C)-orsellinic acid ( 2 ) and (1′- 14 C)-4,6-dihydroxy-2,3-dimethylbenzoic acid ( 3 ) suggest that only the latter compound is a specific precursor of mycophenolic acid; the implication of this result in terms of the early stages of the biosynthetic...

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Veröffentlicht in:Canadian journal of chemistry 1973-03, Vol.51 (5), p.694-697
Hauptverfasser: Bedford, C. T, Knittel, P, Money, T, Phillips, G. T, Salisbury, P
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container_issue 5
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container_title Canadian journal of chemistry
container_volume 51
creator Bedford, C. T
Knittel, P
Money, T
Phillips, G. T
Salisbury, P
description Comparative incorporation experiments with (1′- 14 C)-orsellinic acid ( 2 ) and (1′- 14 C)-4,6-dihydroxy-2,3-dimethylbenzoic acid ( 3 ) suggest that only the latter compound is a specific precursor of mycophenolic acid; the implication of this result in terms of the early stages of the biosynthetic sequence is noted.
doi_str_mv 10.1139/v73-105
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title Biosynthesis of Mycophenolic Acid
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