Oligonucleotide-based therapeutic agents : challenges and advances

Oligonucleotide-based therapeutic agents : challenges and advances

Reviews different ways by which the physicochemical properties of oligonucleotides can be modified to achieve oligonucleotide-based therapeutic agents for clinical applications. Discusses several clinically approved OTAs. Source: National Library of New Zealand Te Puna Matauranga o Aotearoa, license...

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Veröffentlicht in:Chemistry in New Zealand 2020-10, Vol.84 (3), p.119-126
Hauptverfasser: Kurup, Harikrishnan M, Filichev, Vyacheslav V
Format: Artikel
Sprache:eng
Schlagworte:
Oligonucleotides
Therapeutic use
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Zusammenfassung:Reviews different ways by which the physicochemical properties of oligonucleotides can be modified to achieve oligonucleotide-based therapeutic agents for clinical applications. Discusses several clinically approved OTAs. Source: National Library of New Zealand Te Puna Matauranga o Aotearoa, licensed by the Department of Internal Affairs for re-use under the Creative Commons Attribution 3.0 New Zealand Licence.
ISSN:2624-1161
0110-5566