Conservative Oxygen Therapy during Mechanical Ventilation in the ICU
In this study, patients who were undergoing mechanical ventilation received conservative oxygen therapy (i.e., a fraction of inspired oxygen set at 0.21) or usual oxygen therapy with no specific limit, with a lower limit of 90% for oxygen saturation. The number of ventilator-free days did not differ...
Gespeichert in:
| Veröffentlicht in: | The New England journal of medicine 2020-03, Vol.382 (11), p.989-998 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 998 |
|---|---|
| container_issue | 11 |
| container_start_page | 989 |
| container_title | The New England journal of medicine |
| container_volume | 382 |
| creator | Mackle, Diane Bellomo, M. N. Rinaldo Bailey, Michael Beasley, Richard Deane, Adam Eastwood, Glenn Finfer, Simon Freebairn, Ross King, Victoria Linke, Natalie Litton, Edward McArthur, Colin McGuinness, Shay Panwar, Rakshit Young, Paul |
| description | In this study, patients who were undergoing mechanical ventilation received conservative oxygen therapy (i.e., a fraction of inspired oxygen set at 0.21) or usual oxygen therapy with no specific limit, with a lower limit of 90% for oxygen saturation. The number of ventilator-free days did not differ significantly between the two groups. |
| doi_str_mv | 10.1056/NEJMoa1903297 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_mms_n</sourceid><recordid>TN_cdi_mms_nejm_10_1056_NEJMoa1903297</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2376285252</sourcerecordid><originalsourceid>FETCH-LOGICAL-m269t-9a99cceaaa01de60da4bce3af7e9d662439ffab8c6c1fd369b3ee076fe1133283</originalsourceid><addsrcrecordid>eNqN0U1LxDAQBuAgiq4fR69SEEGQapJp0-Yo9RtXL-q1pOnUzdKma9Oq---N7iroybnM5ZlheIeQXUaPGY3Fyd35zbhVTFLgMlkhIxYDhFFExSoZUcrTMEokbJBN56bUF4vkOtkAJhhEwEfkLGutw-5V9eYVg_v3-TPa4GGCnZrNg3LojH0Oxqgnyhqt6uAJbW9qj1sbGBv0Ewyus8dtslap2uHOsm-Rx4vzh-wqvL2_vM5Ob8OGC9mHUkmpNSqlKCtR0FJFhUZQVYKyFIJHIKtKFakWmlUlCFkAIk1EhYwB8BS2yOFi76xrXwZ0fd4Yp7GulcV2cDkHGqcUYmCe7v-h03borL_Oq0TwNOYx92pvqYaiwTKfdaZR3Tz_zseDdAHesGgrpw1ajT_M5xkzKVkEn9HGmem_ksnawfZ-9Oj_o14fLHTTuNzitMkZzT8fnP96MHwADiSShA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2376285252</pqid></control><display><type>article</type><title>Conservative Oxygen Therapy during Mechanical Ventilation in the ICU</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Web of Science - Science Citation Index Expanded - 2020<img src="https://exlibris-pub.s3.amazonaws.com/fromwos-v2.jpg" /></source><source>ProQuest Central UK/Ireland</source><source>New England Journal of Medicine</source><creator>Mackle, Diane ; Bellomo, M. N. Rinaldo ; Bailey, Michael ; Beasley, Richard ; Deane, Adam ; Eastwood, Glenn ; Finfer, Simon ; Freebairn, Ross ; King, Victoria ; Linke, Natalie ; Litton, Edward ; McArthur, Colin ; McGuinness, Shay ; Panwar, Rakshit ; Young, Paul</creator><creatorcontrib>Mackle, Diane ; Bellomo, M. N. Rinaldo ; Bailey, Michael ; Beasley, Richard ; Deane, Adam ; Eastwood, Glenn ; Finfer, Simon ; Freebairn, Ross ; King, Victoria ; Linke, Natalie ; Litton, Edward ; McArthur, Colin ; McGuinness, Shay ; Panwar, Rakshit ; Young, Paul ; The ICU-ROX Investigators and the Australian and New Zealand Intensive Care Society Clinical Trials Group ; Australian New Zealand Intens C ; ICU-ROX Investigators ; ICU-ROX Investigators and the Australian and New Zealand Intensive Care Society Clinical Trials Group ; ICU-ROX Investigators the Australian and New Zealand Intensive Care Society Clinical Trials Group</creatorcontrib><description>In this study, patients who were undergoing mechanical ventilation received conservative oxygen therapy (i.e., a fraction of inspired oxygen set at 0.21) or usual oxygen therapy with no specific limit, with a lower limit of 90% for oxygen saturation. The number of ventilator-free days did not differ significantly between the two groups.</description><identifier>ISSN: 0028-4793</identifier><identifier>EISSN: 1533-4406</identifier><identifier>DOI: 10.1056/NEJMoa1903297</identifier><identifier>PMID: 31613432</identifier><language>eng</language><publisher>WALTHAM: Massachusetts Medical Society</publisher><subject>Adult ; Aged ; Clinical trials ; Cognitive ability ; Confidence intervals ; Consent ; Conservative Treatment ; Female ; General & Internal Medicine ; Humans ; Intensive care ; Intensive Care Units ; Life Sciences & Biomedicine ; Male ; Mechanical ventilation ; Medicine, General & Internal ; Middle Aged ; Mortality ; Oxygen - administration & dosage ; Oxygen Inhalation Therapy - methods ; Oxygen tension ; Oxygen therapy ; Patients ; Quality of life ; Questionnaires ; Ratios ; Respiration, Artificial ; Science & Technology ; Statistical analysis ; Treatment Outcome ; Ventilator Weaning ; Ventilators</subject><ispartof>The New England journal of medicine, 2020-03, Vol.382 (11), p.989-998</ispartof><rights>Copyright © 2019 Massachusetts Medical Society. All rights reserved.</rights><rights>Copyright © 2019 Massachusetts Medical Society.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>true</woscitedreferencessubscribed><woscitedreferencescount>299</woscitedreferencescount><woscitedreferencesoriginalsourcerecordid>wos000519914300005</woscitedreferencesoriginalsourcerecordid><cites>FETCH-LOGICAL-m269t-9a99cceaaa01de60da4bce3af7e9d662439ffab8c6c1fd369b3ee076fe1133283</cites><orcidid>0000-0002-2785-5864 ; 0000-0002-1967-8183 ; 0000-0002-5551-1401 ; 0000-0002-3428-3083 ; 0000-0002-7620-5577 ; 0000-0002-4727-547X ; 0000-0003-0337-406X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.nejm.org/doi/pdf/10.1056/NEJMoa1903297$$EPDF$$P50$$Gmms$$H</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2376285252?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>315,782,786,2764,26112,27933,27934,28257,52391,54073,64394,64396,64398,72478</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31613432$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mackle, Diane</creatorcontrib><creatorcontrib>Bellomo, M. N. Rinaldo</creatorcontrib><creatorcontrib>Bailey, Michael</creatorcontrib><creatorcontrib>Beasley, Richard</creatorcontrib><creatorcontrib>Deane, Adam</creatorcontrib><creatorcontrib>Eastwood, Glenn</creatorcontrib><creatorcontrib>Finfer, Simon</creatorcontrib><creatorcontrib>Freebairn, Ross</creatorcontrib><creatorcontrib>King, Victoria</creatorcontrib><creatorcontrib>Linke, Natalie</creatorcontrib><creatorcontrib>Litton, Edward</creatorcontrib><creatorcontrib>McArthur, Colin</creatorcontrib><creatorcontrib>McGuinness, Shay</creatorcontrib><creatorcontrib>Panwar, Rakshit</creatorcontrib><creatorcontrib>Young, Paul</creatorcontrib><creatorcontrib>The ICU-ROX Investigators and the Australian and New Zealand Intensive Care Society Clinical Trials Group</creatorcontrib><creatorcontrib>Australian New Zealand Intens C</creatorcontrib><creatorcontrib>ICU-ROX Investigators</creatorcontrib><creatorcontrib>ICU-ROX Investigators and the Australian and New Zealand Intensive Care Society Clinical Trials Group</creatorcontrib><creatorcontrib>ICU-ROX Investigators the Australian and New Zealand Intensive Care Society Clinical Trials Group</creatorcontrib><title>Conservative Oxygen Therapy during Mechanical Ventilation in the ICU</title><title>The New England journal of medicine</title><addtitle>NEW ENGL J MED</addtitle><addtitle>N Engl J Med</addtitle><description>In this study, patients who were undergoing mechanical ventilation received conservative oxygen therapy (i.e., a fraction of inspired oxygen set at 0.21) or usual oxygen therapy with no specific limit, with a lower limit of 90% for oxygen saturation. The number of ventilator-free days did not differ significantly between the two groups.</description><subject>Adult</subject><subject>Aged</subject><subject>Clinical trials</subject><subject>Cognitive ability</subject><subject>Confidence intervals</subject><subject>Consent</subject><subject>Conservative Treatment</subject><subject>Female</subject><subject>General & Internal Medicine</subject><subject>Humans</subject><subject>Intensive care</subject><subject>Intensive Care Units</subject><subject>Life Sciences & Biomedicine</subject><subject>Male</subject><subject>Mechanical ventilation</subject><subject>Medicine, General & Internal</subject><subject>Middle Aged</subject><subject>Mortality</subject><subject>Oxygen - administration & dosage</subject><subject>Oxygen Inhalation Therapy - methods</subject><subject>Oxygen tension</subject><subject>Oxygen therapy</subject><subject>Patients</subject><subject>Quality of life</subject><subject>Questionnaires</subject><subject>Ratios</subject><subject>Respiration, Artificial</subject><subject>Science & Technology</subject><subject>Statistical analysis</subject><subject>Treatment Outcome</subject><subject>Ventilator Weaning</subject><subject>Ventilators</subject><issn>0028-4793</issn><issn>1533-4406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>AOWDO</sourceid><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqN0U1LxDAQBuAgiq4fR69SEEGQapJp0-Yo9RtXL-q1pOnUzdKma9Oq---N7iroybnM5ZlheIeQXUaPGY3Fyd35zbhVTFLgMlkhIxYDhFFExSoZUcrTMEokbJBN56bUF4vkOtkAJhhEwEfkLGutw-5V9eYVg_v3-TPa4GGCnZrNg3LojH0Oxqgnyhqt6uAJbW9qj1sbGBv0Ewyus8dtslap2uHOsm-Rx4vzh-wqvL2_vM5Ob8OGC9mHUkmpNSqlKCtR0FJFhUZQVYKyFIJHIKtKFakWmlUlCFkAIk1EhYwB8BS2yOFi76xrXwZ0fd4Yp7GulcV2cDkHGqcUYmCe7v-h03borL_Oq0TwNOYx92pvqYaiwTKfdaZR3Tz_zseDdAHesGgrpw1ajT_M5xkzKVkEn9HGmem_ksnawfZ-9Oj_o14fLHTTuNzitMkZzT8fnP96MHwADiSShA</recordid><startdate>20200312</startdate><enddate>20200312</enddate><creator>Mackle, Diane</creator><creator>Bellomo, M. N. Rinaldo</creator><creator>Bailey, Michael</creator><creator>Beasley, Richard</creator><creator>Deane, Adam</creator><creator>Eastwood, Glenn</creator><creator>Finfer, Simon</creator><creator>Freebairn, Ross</creator><creator>King, Victoria</creator><creator>Linke, Natalie</creator><creator>Litton, Edward</creator><creator>McArthur, Colin</creator><creator>McGuinness, Shay</creator><creator>Panwar, Rakshit</creator><creator>Young, Paul</creator><general>Massachusetts Medical Society</general><general>Massachusetts Medical Soc</general><scope>AOWDO</scope><scope>BLEPL</scope><scope>DTL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>0TZ</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BEC</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K0Y</scope><scope>LK8</scope><scope>M0R</scope><scope>M0T</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>M2P</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-2785-5864</orcidid><orcidid>https://orcid.org/0000-0002-1967-8183</orcidid><orcidid>https://orcid.org/0000-0002-5551-1401</orcidid><orcidid>https://orcid.org/0000-0002-3428-3083</orcidid><orcidid>https://orcid.org/0000-0002-7620-5577</orcidid><orcidid>https://orcid.org/0000-0002-4727-547X</orcidid><orcidid>https://orcid.org/0000-0003-0337-406X</orcidid></search><sort><creationdate>20200312</creationdate><title>Conservative Oxygen Therapy during Mechanical Ventilation in the ICU</title><author>Mackle, Diane ; Bellomo, M. N. Rinaldo ; Bailey, Michael ; Beasley, Richard ; Deane, Adam ; Eastwood, Glenn ; Finfer, Simon ; Freebairn, Ross ; King, Victoria ; Linke, Natalie ; Litton, Edward ; McArthur, Colin ; McGuinness, Shay ; Panwar, Rakshit ; Young, Paul</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-m269t-9a99cceaaa01de60da4bce3af7e9d662439ffab8c6c1fd369b3ee076fe1133283</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Clinical trials</topic><topic>Cognitive ability</topic><topic>Confidence intervals</topic><topic>Consent</topic><topic>Conservative Treatment</topic><topic>Female</topic><topic>General & Internal Medicine</topic><topic>Humans</topic><topic>Intensive care</topic><topic>Intensive Care Units</topic><topic>Life Sciences & Biomedicine</topic><topic>Male</topic><topic>Mechanical ventilation</topic><topic>Medicine, General & Internal</topic><topic>Middle Aged</topic><topic>Mortality</topic><topic>Oxygen - administration & dosage</topic><topic>Oxygen Inhalation Therapy - methods</topic><topic>Oxygen tension</topic><topic>Oxygen therapy</topic><topic>Patients</topic><topic>Quality of life</topic><topic>Questionnaires</topic><topic>Ratios</topic><topic>Respiration, Artificial</topic><topic>Science & Technology</topic><topic>Statistical analysis</topic><topic>Treatment Outcome</topic><topic>Ventilator Weaning</topic><topic>Ventilators</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mackle, Diane</creatorcontrib><creatorcontrib>Bellomo, M. N. Rinaldo</creatorcontrib><creatorcontrib>Bailey, Michael</creatorcontrib><creatorcontrib>Beasley, Richard</creatorcontrib><creatorcontrib>Deane, Adam</creatorcontrib><creatorcontrib>Eastwood, Glenn</creatorcontrib><creatorcontrib>Finfer, Simon</creatorcontrib><creatorcontrib>Freebairn, Ross</creatorcontrib><creatorcontrib>King, Victoria</creatorcontrib><creatorcontrib>Linke, Natalie</creatorcontrib><creatorcontrib>Litton, Edward</creatorcontrib><creatorcontrib>McArthur, Colin</creatorcontrib><creatorcontrib>McGuinness, Shay</creatorcontrib><creatorcontrib>Panwar, Rakshit</creatorcontrib><creatorcontrib>Young, Paul</creatorcontrib><creatorcontrib>The ICU-ROX Investigators and the Australian and New Zealand Intensive Care Society Clinical Trials Group</creatorcontrib><creatorcontrib>Australian New Zealand Intens C</creatorcontrib><creatorcontrib>ICU-ROX Investigators</creatorcontrib><creatorcontrib>ICU-ROX Investigators and the Australian and New Zealand Intensive Care Society Clinical Trials Group</creatorcontrib><creatorcontrib>ICU-ROX Investigators the Australian and New Zealand Intensive Care Society Clinical Trials Group</creatorcontrib><collection>Web of Science - Science Citation Index Expanded - 2020</collection><collection>Web of Science Core Collection</collection><collection>Science Citation Index Expanded</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>Pharma and Biotech Premium PRO</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Database</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>eLibrary</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>New England Journal of Medicine</collection><collection>ProQuest Biological Science Collection</collection><collection>Consumer Health Database</collection><collection>Healthcare Administration Database</collection><collection>Medical Database</collection><collection>Psychology Database</collection><collection>Research Library</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>The New England journal of medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mackle, Diane</au><au>Bellomo, M. N. Rinaldo</au><au>Bailey, Michael</au><au>Beasley, Richard</au><au>Deane, Adam</au><au>Eastwood, Glenn</au><au>Finfer, Simon</au><au>Freebairn, Ross</au><au>King, Victoria</au><au>Linke, Natalie</au><au>Litton, Edward</au><au>McArthur, Colin</au><au>McGuinness, Shay</au><au>Panwar, Rakshit</au><au>Young, Paul</au><aucorp>The ICU-ROX Investigators and the Australian and New Zealand Intensive Care Society Clinical Trials Group</aucorp><aucorp>Australian New Zealand Intens C</aucorp><aucorp>ICU-ROX Investigators</aucorp><aucorp>ICU-ROX Investigators and the Australian and New Zealand Intensive Care Society Clinical Trials Group</aucorp><aucorp>ICU-ROX Investigators the Australian and New Zealand Intensive Care Society Clinical Trials Group</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Conservative Oxygen Therapy during Mechanical Ventilation in the ICU</atitle><jtitle>The New England journal of medicine</jtitle><stitle>NEW ENGL J MED</stitle><addtitle>N Engl J Med</addtitle><date>2020-03-12</date><risdate>2020</risdate><volume>382</volume><issue>11</issue><spage>989</spage><epage>998</epage><pages>989-998</pages><issn>0028-4793</issn><eissn>1533-4406</eissn><abstract>In this study, patients who were undergoing mechanical ventilation received conservative oxygen therapy (i.e., a fraction of inspired oxygen set at 0.21) or usual oxygen therapy with no specific limit, with a lower limit of 90% for oxygen saturation. The number of ventilator-free days did not differ significantly between the two groups.</abstract><cop>WALTHAM</cop><pub>Massachusetts Medical Society</pub><pmid>31613432</pmid><doi>10.1056/NEJMoa1903297</doi><tpages>10</tpages><orcidid>https://orcid.org/0000-0002-2785-5864</orcidid><orcidid>https://orcid.org/0000-0002-1967-8183</orcidid><orcidid>https://orcid.org/0000-0002-5551-1401</orcidid><orcidid>https://orcid.org/0000-0002-3428-3083</orcidid><orcidid>https://orcid.org/0000-0002-7620-5577</orcidid><orcidid>https://orcid.org/0000-0002-4727-547X</orcidid><orcidid>https://orcid.org/0000-0003-0337-406X</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0028-4793 |
| ispartof | The New England journal of medicine, 2020-03, Vol.382 (11), p.989-998 |
| issn | 0028-4793 1533-4406 |
| language | eng |
| recordid | cdi_mms_nejm_10_1056_NEJMoa1903297 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Web of Science - Science Citation Index Expanded - 2020<img src="https://exlibris-pub.s3.amazonaws.com/fromwos-v2.jpg" />; ProQuest Central UK/Ireland; New England Journal of Medicine |
| subjects | Adult Aged Clinical trials Cognitive ability Confidence intervals Consent Conservative Treatment Female General & Internal Medicine Humans Intensive care Intensive Care Units Life Sciences & Biomedicine Male Mechanical ventilation Medicine, General & Internal Middle Aged Mortality Oxygen - administration & dosage Oxygen Inhalation Therapy - methods Oxygen tension Oxygen therapy Patients Quality of life Questionnaires Ratios Respiration, Artificial Science & Technology Statistical analysis Treatment Outcome Ventilator Weaning Ventilators |
| title | Conservative Oxygen Therapy during Mechanical Ventilation in the ICU |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-02T17%3A33%3A28IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_mms_n&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Conservative%20Oxygen%20Therapy%20during%20Mechanical%20Ventilation%20in%20the%20ICU&rft.jtitle=The%20New%20England%20journal%20of%20medicine&rft.au=Mackle,%20Diane&rft.aucorp=The%20ICU-ROX%20Investigators%20and%20the%20Australian%20and%20New%20Zealand%20Intensive%20Care%20Society%20Clinical%20Trials%20Group&rft.date=2020-03-12&rft.volume=382&rft.issue=11&rft.spage=989&rft.epage=998&rft.pages=989-998&rft.issn=0028-4793&rft.eissn=1533-4406&rft_id=info:doi/10.1056/NEJMoa1903297&rft_dat=%3Cproquest_mms_n%3E2376285252%3C/proquest_mms_n%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2376285252&rft_id=info:pmid/31613432&rfr_iscdi=true |