Conservative Oxygen Therapy during Mechanical Ventilation in the ICU

In this study, patients who were undergoing mechanical ventilation received conservative oxygen therapy (i.e., a fraction of inspired oxygen set at 0.21) or usual oxygen therapy with no specific limit, with a lower limit of 90% for oxygen saturation. The number of ventilator-free days did not differ...

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Veröffentlicht in:	The New England journal of medicine 2020-03, Vol.382 (11), p.989-998
Hauptverfasser:	Mackle, Diane, Bellomo, M. N. Rinaldo, Bailey, Michael, Beasley, Richard, Deane, Adam, Eastwood, Glenn, Finfer, Simon, Freebairn, Ross, King, Victoria, Linke, Natalie, Litton, Edward, McArthur, Colin, McGuinness, Shay, Panwar, Rakshit, Young, Paul
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Clinical trials Cognitive ability Confidence intervals Consent Conservative Treatment Female General & Internal Medicine Humans Intensive care Intensive Care Units Life Sciences & Biomedicine Male Mechanical ventilation Medicine, General & Internal Middle Aged Mortality Oxygen - administration & dosage Oxygen Inhalation Therapy - methods Oxygen tension Oxygen therapy Patients Quality of life Questionnaires Ratios Respiration, Artificial Science & Technology Statistical analysis Treatment Outcome Ventilator Weaning Ventilators
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Zusammenfassung:	In this study, patients who were undergoing mechanical ventilation received conservative oxygen therapy (i.e., a fraction of inspired oxygen set at 0.21) or usual oxygen therapy with no specific limit, with a lower limit of 90% for oxygen saturation. The number of ventilator-free days did not differ significantly between the two groups.
ISSN:	0028-4793 1533-4406
DOI:	10.1056/NEJMoa1903297