Glandular Lesion of the Uterine Cervix

Histopathological diagnosis of glandular lesions of the uterine cervix was described with the microscopic photographs by Dr. Silverberg. Firstly, the clinical points about how to make a diagnosis of adenocarcinoma in situ were presented comparing the histology about glandular dysplasia and tubal metaplasia. Then, the differences of histology among invasive adenocarcinoma of endocervical type, invasive adenocarcinoma of endometiroid type, clear cell adenocarcinoma, and papillary serous carcinoma were described with several photographs of histology. Next, histological characteristics about minimal deviation adenocarcinoma (MDA: adenoma malignum) were demonstrated comparing with benign endocervical lesion such as lobular glandular hyperplasia. The immunohistochemistry using HIK1073 seemed useful to make a diagnosis of MDA. It is also described about ovarian lesions which are called sex cord tumors with annual tubules (SCTAT) in Peutz-Jeghers syndrome. Finally the lecture was closed describing histological features about mesonephritic adenocarcinoma, glassy cell carcinoma, adenoid basal carcinoma, and adenoid cystic carcinoma.