Determination of Copper- Containing Amine Oxidase (Diamine Oxidase) Activity

(Summary)The historical background, laboratory determinations, and clinical applications of diamine oxidase (DAO) are reviewed. DAO is a copper-containing globulin, which takes part in the oxidation of diamines such as histamine, putrescine, and others. This oxidative activity is considered as the b...

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Veröffentlicht in:Journal of Analytical Bio-Science 1992-12, Vol.15 (4/5), p.174-181
Hauptverfasser: Miyuki Takayanagi, Tamotsu Yashiro
Format: Artikel
Sprache:eng ; jpn
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Zusammenfassung:(Summary)The historical background, laboratory determinations, and clinical applications of diamine oxidase (DAO) are reviewed. DAO is a copper-containing globulin, which takes part in the oxidation of diamines such as histamine, putrescine, and others. This oxidative activity is considered as the basic reaction for the DAO assay. Measurement of DAO activity in blood serum is useful during normal pregnancy and for determining the measurement of patients with lung carcinoma and histaminase producing tumores.
ISSN:0913-3763