Bioactive Secondary Metabolites with Unique Aromatic and Heterocyclic Structures Obtained from Terrestrial Actinomycetes Species

Natural products from actinomycetes are important and valuable sources for drug discovery and the development of biological tools. The present review describes our recent study on the isolation of new natural products mainly possessing heterocyclic and aromatic ring structures with biological effect...

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Veröffentlicht in:Chemical and Pharmaceutical Bulletin 2016-07, Vol.64 (7), p.668-675
Hauptverfasser: Mohamed S.Abdelfattaha, b, Midori A.Araia, Masami Ishibashia
Format: Artikel
Sprache:jpn
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Zusammenfassung:Natural products from actinomycetes are important and valuable sources for drug discovery and the development of biological tools. The present review describes our recent study on the isolation of new natural products mainly possessing heterocyclic and aromatic ring structures with biological effects on cancer-related cellular pathways such as tumor necrosis factor-α-related apoptosis-inducing ligand (TRAIL) and Wnt signaling.
ISSN:0009-2363