Pyrazolidine Derivatives with Heteroaryl Urea as Dipeptidyl Peptidase IV Inhibitors

In the continuation of efforts to modify the structure of our novel DP-IV inhibitors, a series of pyrazolidine derivatives with heteroaryl urea was synthesized and evaluated for their ability to inhibit dipeptidyl peptidase IV (DP-IV).

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Veröffentlicht in:Chemical & Pharmaceutical Bulletin 2005, Vol.53 (8), p.1048-1050
Hauptverfasser: Jin Hee AHN, a, Sun Ho JUNGa, Jin Ah KIMa, Seog Beom SONGc, Soon Ji KWONc, Kwang Rok KIMa, Sang Dal RHEEa, Sung-Dae PARKb, Jae Mok LEEc, Sung Soo KIMa, Hyae Gyeong CHEONa
Format: Artikel
Sprache:jpn
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Zusammenfassung:In the continuation of efforts to modify the structure of our novel DP-IV inhibitors, a series of pyrazolidine derivatives with heteroaryl urea was synthesized and evaluated for their ability to inhibit dipeptidyl peptidase IV (DP-IV).
ISSN:0009-2363