Cymbopogonol from Cymbopogon citratus and Its Biological Activity

Cymbopogonol from Cymbopogon citratus and Its Biological Activity

Phytochemical investigation of the leaves of Cymbopogon citratus led to the isolation of 10 compounds (1-10), including one known triterpene, cymbopogonol (1). The absolute configurations of 1 were determined by X-ray crystallography of the corresponding p-bromobenzoate derivative (1a). Compound 1 s...

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Veröffentlicht in:Shoyakugaku Zasshi 2017/08/20, Vol.71(2), pp.98-99
Hauptverfasser: Matsuo, Yukiko, Kubota, Ayana, Masimo, Ryo, Fukaya, Haruhiko, Inaba, Niro, Mimaki, Yoshihiro
Format: Artikel
Sprache:eng ; jpn
Schlagworte:
Cymbopogon citratus
cymbopogonol
Gramineae
pancreatic lipase
triterpene
X-ray crystallography
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Zusammenfassung:Phytochemical investigation of the leaves of Cymbopogon citratus led to the isolation of 10 compounds (1-10), including one known triterpene, cymbopogonol (1). The absolute configurations of 1 were determined by X-ray crystallography of the corresponding p-bromobenzoate derivative (1a). Compound 1 showed pancreatic lipase inhibitor activity in vitro and reduced serum triglyceride levels in mice fed a high-fat diet compared with the control group.
ISSN:1349-9114
2433-8486
DOI:10.24684/jspharm.71.2_98