PB2-5 Effect of Ultra-Violet Light Exposure on Some Immunological Parameters in Humans

This study assesses the effects of UV+or UV-conditions, under the sun light environment, on selected immunological parameters with 14 healthy young men (aged 21.9±1.6yr). Subjects were divided into UV + group without and UV - group with clothing. They stayed outside between 11:00 h to 14:00 h. Just before the start/end of UV light exposure, blood sample was taken for later immunological assay of WBC, phagocytosis, IL-6, IL-10, CD4+CD25+T cells, and NK-cells. The results were as follows：1) WBC and Phagocytosis did not vary between both groups；2) CD4+CD25+ T cells tended to decrease under UV-group；3) NK cells were significantly lower under UV+ compared to UV-exposure；4) IL-6 were significantly higher under UV + conditions；5) Sympathetic nervous system was activated during exposure to UV. These findings are discussed in terms of immune and autonomic nervous system under the influence of UV light exposure.