HIV replication and tuberculosis risk among people living with HIV in Europe: A multicohort analysis, 1983-2015

HIV replication and tuberculosis risk among people living with HIV in Europe: A multicohort analysis, 1983-2015

INTRODUCTION: HIV replication leads to a change in lymphocyte phenotypes that impairs immune protection against opportunistic infections. We examined current HIV replication as an independent risk factor for tuberculosis (TB). METHODS: We included people living with HIV from 25 European cohorts 1983...

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Veröffentlicht in:PloS one 2024-01, Vol.19 (10)
Hauptverfasser: Atkinson, Andrew, Kraus, David, Banholzer, Nicolas, Miro, Jose M, Reiss, Peter, Kirk, Ole, Mussini, Cristina, Morlat, Philippe, Podlekareva, Daria, Grant, Alison D, Sabin, Caroline, van der Valk, Marc, Le Moing, Vincent, Meyer, Laurence, Seng, Remonie, Castagna, Antonella, Obel, Niels, Antoniadou, Anastasia, Salmon, Dominique, Zwahlen, Marcel, Egger, Matthias, de Wit, Stephane, Furrer, Hansjakob, Fenner, Lukas, Opportunistic Infections Project Working Group of the Collaborat
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Sprache:eng
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Zusammenfassung:INTRODUCTION: HIV replication leads to a change in lymphocyte phenotypes that impairs immune protection against opportunistic infections. We examined current HIV replication as an independent risk factor for tuberculosis (TB). METHODS: We included people living with HIV from 25 European cohorts 1983-2015. Individuals
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0312035