Methodology for Whole-Genome Sequencing of Methicillin-Resistant Staphylococcus aureus Isolates in a Routine Hospital Microbiology Laboratory

Methodology for Whole-Genome Sequencing of Methicillin-Resistant Staphylococcus aureus Isolates in a Routine Hospital Microbiology Laboratory

There is growing evidence for the value of bacterial whole-genome sequencing in hospital outbreak investigations. Our aim was to develop methods that support efficient and accurate low-throughput clinical sequencing of methicillin-resistant Staphylococcus aureus (MRSA) isolates.

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Veröffentlicht in:Journal of Clinical Microbiology 2019-03, Vol.57 (6)
Hauptverfasser: Raven, Kathy E, Blane, Beth, Leek, Danielle, Churcher, Carol, Kokko-Gonzales, Paula, Pugazhendhi, Dhamayanthi, Fraser, Louise, Betley, Jason, Parkhill, Julian, Peacock, Sharon J
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Sprache:eng
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Zusammenfassung:There is growing evidence for the value of bacterial whole-genome sequencing in hospital outbreak investigations. Our aim was to develop methods that support efficient and accurate low-throughput clinical sequencing of methicillin-resistant Staphylococcus aureus (MRSA) isolates.
ISSN:0095-1137
DOI:10.1128/jcm.00180-19