Optimizing surgical treatment of rare cutaneous malignancies: rare cancers are not so rare at all

Cutaneous malignancies are the most frequent human malignancy with an increasing incidence reaching epidemic proportions among Caucasians in Europe, America and Australia. The most common cutaneous malignancy is basal cell carcinoma, followed by squamous cell carcinoma (cSCC) and melanoma.(1-3) There are also other, less common cutaneous malignancies which consist of less than 5% of the cutaneous malignancies. Some of these rare cutaneous malignancies are still considered skin cancer such as sebaceous carcinoma, while others are classified as soft tissue sarcoma (DFSP, angiosarcoma). In this thesis, I aimed to analyse outcome after surgical procedures for rare cutaneous malignancies and the rare locally advanced cases of cSCC.