A bioorthogonal chemistry approach to the study of biomolecules in their ultrastructural cellular context

A bioorthogonal chemistry approach to the study of biomolecules in their ultrastructural cellular context

In this thesis the combinatorial use of bioorthogonal labelling and Electron Microscopy (EM)-based imaging techniques is explored to enable observations of specific molecular targets in their ultrastructural context within the cell.

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Bibliographische Detailangaben
1. Verfasser: Elsland, D.M. van
Format: Dissertation
Sprache:eng
Schlagworte:
Bioorthogonal chemistry
Correlative light and electron microscopy
Electron microscopy
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Beschreibung
Zusammenfassung:In this thesis the combinatorial use of bioorthogonal labelling and Electron Microscopy (EM)-based imaging techniques is explored to enable observations of specific molecular targets in their ultrastructural context within the cell.