Drosophila Invasive Tumors: A Model for Understanding Metastasis

Drosophila Invasive Tumors: A Model for Understanding Metastasis

Inactivation of Drosophila tumor suppressor genes can cause excessive proliferation and, in some cases, neoplastic growth. Neoplastic growth in Drosophila tissues can also be followed by metastasis upon transplantation into hosts or in vivo. Recently, we have shown that metastatic tumors of Drosophi...

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Veröffentlicht in:Cell cycle (Georgetown, Tex.) Tex.), 2004-01, Vol.3 (1), p.37-39
Hauptverfasser: Woodhouse, Elisa C., Liotta, Lance A.
Format: Artikel
Sprache:eng
Schlagworte:
Binding
Biology
Bioscience
Calcium
Cancer
Cell
Cycle
Landes
Organogenesis
Proteins
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Zusammenfassung:Inactivation of Drosophila tumor suppressor genes can cause excessive proliferation and, in some cases, neoplastic growth. Neoplastic growth in Drosophila tissues can also be followed by metastasis upon transplantation into hosts or in vivo. Recently, we have shown that metastatic tumors of Drosophila can provide a model in which to identify genes that are involved in the metastatic process.
ISSN:1538-4101
1551-4005
DOI:10.4161/cc.3.1.636