A clinical scoring system to predict long-term arthralgia in Chikungunya disease: A cohort study

A clinical scoring system to predict long-term arthralgia in Chikungunya disease: A cohort study

BACKGROUND: Chikungunya virus (CHIKV) has caused worldwide epidemics that impose a major burden on health systems. Approximately half of infected individuals develop chronic debilitating arthralgia, affecting their quality of life. Here, we identified the relevant clinical and demographic variables...

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Veröffentlicht in:PLOS NEGLECTED TROPICAL DISEASES 2020-07, Vol.14 (7)
Hauptverfasser: de Moraes, Laise, Cerqueira-Silva, Thiago, Nobrega, Victor, Akrami, Kevan, Santos, Luciane Amorim, Orge, Cibele, Casais, Paula, Cambui, Lais, Pontello Rampazzo, Rita de Cassia, Trinta, Karen Soares, Montalbano, Camila Amato, Teixeira, Maria Jania, Cavalcante, Luciano Pamplona, Andrade, Bruno B, Cunha, Rivaldo Venancio, Krieger, Marco Aurelio, Barral-Netto, Manoel, Barral, Aldina, Khouri, Ricardo, Boaventura, Viviane Sampaio
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Sprache:eng
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Zusammenfassung:BACKGROUND: Chikungunya virus (CHIKV) has caused worldwide epidemics that impose a major burden on health systems. Approximately half of infected individuals develop chronic debilitating arthralgia, affecting their quality of life. Here, we identified the relevant clinical and demographic variables in the acute phase of CHIKV infection prospectively linked to chronic arthralgia to elaborate a prognostic scoring system. METHODS: Acute CHIKV infection cases (n = 134) confirmed by serology or molecular test were examined
ISSN:1935-2735