Gestational choriocarcinoma

Gestational choriocarcinoma accounts for 5% of gestational trophoblastic neoplasms. Approximately 50%, 25%, and 25% of gestational choriocarcinoma occur after molar pregnancies, term pregnancies, and other gestational events, respectively. The FIGO scoring system categorizes patients into low (score...

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Veröffentlicht in:INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER 2023-10, Vol.33 (10), p.1504-1514
Hauptverfasser: Bogani, Giorgio, Ray-Coquard, Isabelle, Mutch, David, Vergote, Ignace, Ramirez, Pedro T, Prat, Jaime, Concin, Nicole, Ngoi, Natalie Yan Li, Coleman, Robert L, Enomoto, Takayuki, Takehara, Kazuhiro, Denys, Hannelore, Lorusso, Domenica, Takano, Masashi, Sagae, Satoru, Wimberger, Pauline, Segev, Yakir, Kim, Se Ik, Kim, Jae-Weon, Herrera, Fernanda, Mariani, Andrea, Brooks, Rebecca A, Tan, David, Paolini, Biagio, Chiappa, Valentina, Longo, Mariangela, Raspagliesi, Francesco, Panici, Pierluigi Benedetti, Di Donato, Violante, Caruso, Giuseppe, Colombo, Nicoletta, Pignata, Sandro, Zannoni, Gianfranco, Scambia, Giovanni, Monk, Bradley J
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Sprache:eng
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Zusammenfassung:Gestational choriocarcinoma accounts for 5% of gestational trophoblastic neoplasms. Approximately 50%, 25%, and 25% of gestational choriocarcinoma occur after molar pregnancies, term pregnancies, and other gestational events, respectively. The FIGO scoring system categorizes patients into low (score 0 to 6) and high risk (score 7 or more) choriocarcinoma. Single-agent and multi-agent chemotherapy are used in low- and high-risk patients, respectively. Chemotherapy for localized disease has a goal of eradication of disease without surgery and is associated with favorable prognosis and fertility preservation. Most patients with gestational choriocarcinoma are cured with chemotherapy; however, some (
ISSN:1048-891X