Association of Early MRI Characteristics With Subsequent Epilepsy and Neurodevelopmental Outcomes in Children With Tuberous Sclerosis Complex

Association of Early MRI Characteristics With Subsequent Epilepsy and Neurodevelopmental Outcomes in Children With Tuberous Sclerosis Complex

BACKGROUND AND OBJECTIVES: Multiple factors have been found to contribute to the high risk of epilepsy in infants with tuberous sclerosis complex (TSC), including evolution of EEG abnormalities, TSC gene variant, and MRI characteristics. The aim of this prospective multicenter study was to identify...

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Veröffentlicht in:NEUROLOGY 2022-03, Vol.98 (12), p.E1216-E1225
Hauptverfasser: Hulshof, Hanna M, Kuijf, Hugo J, Kotulska, Katarzyna, Curatolo, Paolo, Weschke, Bernhard, Riney, Kate, Krsek, Pavel, Feucht, Martha, Nabbout, Rima, Lagae, Lieven, Jansen, Anna, Otte, Wim M, Lequin, Maarten H, Sijko, Kamil, Benvenuto, Arianna, Hertzberg, Christoph, Benova, Barbora, Scholl, Theresa, De Ridder, Jessie, Aronica, Eleonora M.A, Kwiatkowski, David J, Jozwiak, Sergiusz, Jurkiewicz, Elzbieta, Braun, Kees, Jansen, Floor E
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Sprache:eng
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Zusammenfassung:BACKGROUND AND OBJECTIVES: Multiple factors have been found to contribute to the high risk of epilepsy in infants with tuberous sclerosis complex (TSC), including evolution of EEG abnormalities, TSC gene variant, and MRI characteristics. The aim of this prospective multicenter study was to identify early MRI biomarkers of epilepsy in infants with TSC aged
ISSN:0028-3878