Age-related changes in the fractal dimension of the retinal microvasculature, effects of cardiovascular risk factors and smoking behaviour

PURPOSE: This cross-sectional study investigates the association between retinal vessel complexity and age and studies the effects of cardiovascular health determinants. METHODS: Retinal vessel complexity was assessed by calculating the box-counting fractal dimension (Df ) from digital fundus photog...

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Veröffentlicht in:ACTA OPHTHALMOLOGICA 2021-11, Vol.100 (5), p.E1112-E1119
Hauptverfasser: Lemmens, Sophie, Luyts, Martial, Gerrits, Nele, Ivanova, Anna, Landtmeeters, Charlien, Peeters, Reinout, Simons, Anne-Sophie, Vercauteren, Julie, Sunaric-Megevand, Gordana, Van Keer, Karel, Molenberghs, Geert, De Boever, Patrick, Stalmans, Ingeborg
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Sprache:eng
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Zusammenfassung:PURPOSE: This cross-sectional study investigates the association between retinal vessel complexity and age and studies the effects of cardiovascular health determinants. METHODS: Retinal vessel complexity was assessed by calculating the box-counting fractal dimension (Df ) from digital fundus photographs of 850 subjects (3-97 years). All photographs were labelled as 'non-pathological' by the treating ophthalmologist. RESULTS: Statistical models showed a significantly decreasing relationship between age and Df (linear: R-squared = 0.1897, p 
ISSN:1755-375X