Reference Human Rotavirus A Genome Sequence from a Previously Vaccinated Child with Diarrhea in Nigeria

Reference Human Rotavirus A Genome Sequence from a Previously Vaccinated Child with Diarrhea in Nigeria

In 2018, a 26-month-old girl, fully vaccinated with Rotarix in 2016, presented with fever, diarrhea, and vomiting. A rapid test showed that her feces contained rotavirus A (RVA). VP7 reverse transcription-PCR (RT-PCR) and Illumina sequencing showed that a G1P[8] strain with a Wa-like genotype conste...

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Veröffentlicht in:MICROBIOLOGY RESOURCE ANNOUNCEMENTS 2020-01, Vol.9 (5)
Hauptverfasser: Faleye, T.O.C, George, U.E, Simsek, C, Arowolo, O.A, Adewumi, O.M, Matthijnssens, J, Adeniji, J.A
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Sprache:eng
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Zusammenfassung:In 2018, a 26-month-old girl, fully vaccinated with Rotarix in 2016, presented with fever, diarrhea, and vomiting. A rapid test showed that her feces contained rotavirus A (RVA). VP7 reverse transcription-PCR (RT-PCR) and Illumina sequencing showed that a G1P[8] strain with a Wa-like genotype constellation was the etiologic agent. This is the first near-complete RVA genome sequence from Nigeria.
ISSN:2576-098X
2576-098X