Differential Time Course of Microstructural White Matter in Patients With Psychotic Disorder and Individuals at Risk: A 3-Year Follow-up Study

Differential Time Course of Microstructural White Matter in Patients With Psychotic Disorder and Individuals at Risk: A 3-Year Follow-up Study

Although widespread reduced white matter (WM) integrity is a consistent finding in cross-sectional diffusion tensor imaging (DTI) studies of schizophrenia, little is known about the course of these alterations. This study examined to what degree microstructural WM alterations display differential tr...

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Veröffentlicht in:Schizophrenia Bulletin 2017, Vol.43 (1), p.160-170
Hauptverfasser: Domen, Patrick, Peeters, Sanne, Michielse, Stijn, Gronenschild, Ed, Viechtbauer, Wolfgang, Roebroeck, Alard, Os, Jim van, Marcelis, Machteld
Format: Artikel
Sprache:eng
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Zusammenfassung:Although widespread reduced white matter (WM) integrity is a consistent finding in cross-sectional diffusion tensor imaging (DTI) studies of schizophrenia, little is known about the course of these alterations. This study examined to what degree microstructural WM alterations display differential trajectories over time as a function of level of psychosis liability.
ISSN:0586-7614