Validation of the DAPT score in patients randomized to 6 or 12 months clopidogrel after predominantly second-generation drug-eluting stents

Validation of the DAPT score in patients randomized to 6 or 12 months clopidogrel after predominantly second-generation drug-eluting stents

The DAPT score is a recently-proposed decision tool for guiding optimal duration of dual antiplatelet therapy (DAPT). It showed modest accuracy in prior derivation and validation cohorts of patients with ≥12 months DAPT. This study was aimed to evaluate the validity of the DAPT score in a cohort of...

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Veröffentlicht in:Thrombosis and Haemostasis 2017, Vol.117 (10), p.1989-1999
Hauptverfasser: Harada, Yukinori, Michel, Jonathan, Lohaus, Raphaela, Mayers, Katharina, Emmer, Roberto, Lahmann, Anna Lena, Colleran, Roisin, Giacoppo, Daniele, Wolk, Annabelle, ten Berg, Jurrien M, Neumann, Franz-Josef, Hans, Yaling, Adriaenssens, Tom, Toelg, Ralph, Seyfarth, Melchior, Maeng, Michael, Zrenner, Bernhard, Jacobshagen, Claudius, Wohrle, Jochen, Kufner, Sebastian, Morath, Tanja, Ibrahim, Tareq, Bernlochner, Isabel, Fischer, Marcus, Schunkert, Heribert, Laugwitz, Karl-Ludwig, Mehilli, Julinda, Byrnes, Robert A, Kastrati, Adnan, Schulz-Schuepke, Stefanie
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Sprache:eng
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Zusammenfassung:The DAPT score is a recently-proposed decision tool for guiding optimal duration of dual antiplatelet therapy (DAPT). It showed modest accuracy in prior derivation and validation cohorts of patients with ≥12 months DAPT. This study was aimed to evaluate the validity of the DAPT score in a cohort of patients with 6 or 12 months DAPT after implantation of predominantly second-generation drug-eluting stents. We analyzed data of patients enrolled in the ISAR-SAFE trial. Patients were classified into low (
ISSN:0340-6245