Een hardnekkig geval van 'reuma' met vermagering en rode ogen

A stubborn case of 'rheumatism' with weight loss and red eyes. A 51-year-old man was sent to the department of internal medicine with diarrhea, extreme weight loss, severe fatigue, night sweats and a shivery feeling with subfebrility. His medical history reveals ungoing arthralgias, refractory to anti-rheumatic therapy. A gastroduodenoscopy reveals the macroscopic image of Whipple 's disease. polymerase chain reaction (PCR) analyses by Dr. Raoult at his laboratory in Marseille confim1ed this assumption. The epidemiology, etiology and pathofysiology of Whipple 's disease are briefly discussed. Furthermore the clinical manifestations, the diagnosis and the treatment are explained.