Body weight, gender, and pregnancy affect enantiomer-specific ketorolac pharmacokinetics
Although ketorolac analgesia is linked only to the S-enantiomer, there is limited information on the stereo-selective pharmacokinetics of ketorolac. We studied the stereo-selective pharmacokinetics of ketorolac in a pooled dataset of two studies, with women at delivery and 4-5 months postpartum, and...
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Veröffentlicht in: | British Journal of Clinical Pharmacology 2017-09, Vol.83 (9), p.1966-1975 |
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container_end_page | 1975 |
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container_issue | 9 |
container_start_page | 1966 |
container_title | British Journal of Clinical Pharmacology |
container_volume | 83 |
creator | Välitalo, Pyry A Kemppainen, Heidi Kulo, Aida Smits, Anne Van Calsteren, Kristel Olkkola, Klaus T de Hoon, Jan Knibbe, Catherijne A.J Allegaert, Karel |
description | Although ketorolac analgesia is linked only to the S-enantiomer, there is limited information on the stereo-selective pharmacokinetics of ketorolac. We studied the stereo-selective pharmacokinetics of ketorolac in a pooled dataset of two studies, with women at delivery and 4-5 months postpartum, and males and non-pregnant females. |
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source | Wiley Free Content; Lirias (KU Leuven Association); Wiley Online Library Journals Frontfile Complete; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
title | Body weight, gender, and pregnancy affect enantiomer-specific ketorolac pharmacokinetics |
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