Multicenter validation of CSF neurofilaments as diagnostic biomarkers for ALS

Multicenter validation of CSF neurofilaments as diagnostic biomarkers for ALS

Neurofilaments are leading neurochemical biomarkers for amyotrophic lateral sclerosis (ALS). Here, we investigated the effect of preanalytical factors on neurofilament concentrations in cerebrospinal fluid (CSF) in a "reverse" round-robin with 15 centers across Europe/U.S.

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Veröffentlicht in:Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 2016-07, Vol.17 (5-6), p.404-413
Hauptverfasser: Oeckl, Patrick, Jardel, Claude, Salachas, François, Lamari, Foudil, Andersen, Peter M, Bowser, Robert, de Carvalho, Mamede, Costa, Júlia, Van Damme, Philip, Gray, Elizabeth, Grosskreutz, Julian, Hernández-Barral, María, Herukka, Sanna-Kaisa, Huss, André, Jeromin, Andreas, Kirby, Janine, Kuzma-Kozakiewicz, Magdalena, Amador, Maria Del Mar, Mora, Jesús S, Morelli, Claudia, Muckova, Petra, Petri, Susanne, Poesen, Koen, Rhode, Heidrun, Rikardsson, Anna-Karin, Robberecht, Wim, Rodríguez Mahillo, Ana I, Shaw, Pamela, Silani, Vincenzo, Steinacker, Petra, Turner, Martin R, Tüzün, Erdem, Yetimler, Berrak, Ludolph, Albert C, Otto, Markus
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Sprache:eng
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Zusammenfassung:Neurofilaments are leading neurochemical biomarkers for amyotrophic lateral sclerosis (ALS). Here, we investigated the effect of preanalytical factors on neurofilament concentrations in cerebrospinal fluid (CSF) in a "reverse" round-robin with 15 centers across Europe/U.S.
ISSN:2167-8421