Chemotherapy induced intestinal mucosal barrier damage: a cause of falsely elevated serum 1.3-beta-d-glucan levels?

Chemotherapy induced intestinal mucosal barrier damage: a cause of falsely elevated serum 1.3-beta-d-glucan levels?

Blood citrulline and intestinal fatty acid binding protein were determined as biomarkers for intestinal mucositis. Biomarker levels were correlated with corresponding serum 1,3-beta-d-glucan levels in 56 samples obtained from 33 cases with underlying hematological malignancies receiving induction ch...

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Veröffentlicht in:Journal of Clinical Microbiology 2016-03, Vol.54 (3), p.798-801
Hauptverfasser: Prattes, J, Raggam, R.B, Vanstraelen, K, Rabensteiner, J, Hoegenauer, C, Krause, R, Prueller, F, Woelfler, A, Spriet, Isabel, Hoenigl, M
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Sprache:eng
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Zusammenfassung:Blood citrulline and intestinal fatty acid binding protein were determined as biomarkers for intestinal mucositis. Biomarker levels were correlated with corresponding serum 1,3-beta-d-glucan levels in 56 samples obtained from 33 cases with underlying hematological malignancies receiving induction chemotherapy. No correlation between biomarkers of intestinal mucositis and BDG levels was observed.
ISSN:0095-1137