Invasive pneumococcal disease in children can reveal a primary immunodeficiency

Invasive pneumococcal disease in children can reveal a primary immunodeficiency

About 10% of pediatric patients with invasive pneumococcal disease (IPD) die from the disease. Some primary immunodeficiencies (PIDs) are known to confer predisposition to IPD. However, a systematic search for these PIDs has never been carried out in children presenting with IPD.

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Veröffentlicht in:Clinical Infectious Diseases 2014-07, Vol.59 (2), p.244-51
Hauptverfasser: Gaschignard, Jean, Levy, Corinne, Chrabieh, Maya, Boisson, Bertrand, Bost-Bru, Cécile, Dauger, Stéphane, Dubos, François, Durand, Philippe, Gaudelus, Joël, Gendrel, Dominique, Gras Le Guen, Christèle, Grimprel, Emmanuel, Guyon, Gaël, Jeudy, Catherine, Jeziorski, Eric, Leclerc, Francis, Léger, Pierre-Louis, Lesage, Fabrice, Lorrot, Mathie, Pellier, Isabelle, Pinquier, Didier, de Pontual, Loïc, Sachs, Philippe, Thomas, Caroline, Tissières, Pierre, Valla, Frédéric V, Desprez, Philippe, Frémeaux-Bacchi, Véronique, Varon, Emmanuelle, Bossuyt, Xavier, Cohen, Robert, Abel, Laurent, Casanova, Jean-Laurent, Puel, Anne, Picard, Capucine
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Sprache:eng
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Zusammenfassung:About 10% of pediatric patients with invasive pneumococcal disease (IPD) die from the disease. Some primary immunodeficiencies (PIDs) are known to confer predisposition to IPD. However, a systematic search for these PIDs has never been carried out in children presenting with IPD.
ISSN:1058-4838