Short-term modulation of extracellular signal-regulated kinase 1/2 and stress-activated protein kinase/c-Jun NH2-terminal kinase in pancreatic islets by glucose and palmitate: possible involvement of ceramide

The effect of glucose and palmitate on the phosphorylation of proteins associated with cell growth and survival (extracellular signal-regulated kinase 1/2 [ERK1/2] and stress-activated protein kinase/c-Jun NH2-terminal kinase [SAPK/JNK]) and on the expression of immediate early genes was investigate...

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Veröffentlicht in:Pancreas 2009-07, Vol.38 (5), p.585-92
Hauptverfasser: Nogueira, Tatiane C, Graciano, Maria Fernanda R, Anhê, Gabriel F, Curi, Rui, Bordin, Silvana, Carpinelli, Angelo R
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Sprache:eng
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Zusammenfassung:The effect of glucose and palmitate on the phosphorylation of proteins associated with cell growth and survival (extracellular signal-regulated kinase 1/2 [ERK1/2] and stress-activated protein kinase/c-Jun NH2-terminal kinase [SAPK/JNK]) and on the expression of immediate early genes was investigated.
ISSN:0885-3177