Anti-photoaging Constituents from Eurya emarginata Leaves

Eurya emarginata is an evergreen tree growing in the southern regions of Korea including Jeju Island. In this study, antioxidant and anti-photoaging effects were investigated with the extracts of E. emarginata leaves. As comparative studies with the extract and five solvent fractions, the EtOAc frac...

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Veröffentlicht in:Journal of the Korean Chemical Society 2023-04, Vol.67 (2), p.150-155
Hauptverfasser: Sung Chun Kim, So Yeon Oh, Hyejin Hyeon, Boram Go, Seon-A Yoon, Yong-Hwan Jung, Nam Ho Lee, Young-Min Ham
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Sprache:eng
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Zusammenfassung:Eurya emarginata is an evergreen tree growing in the southern regions of Korea including Jeju Island. In this study, antioxidant and anti-photoaging effects were investigated with the extracts of E. emarginata leaves. As comparative studies with the extract and five solvent fractions, the EtOAc fraction showed the most effective DPPH and ABTS+ radical scavenging activities. The EtOAc fraction also inhibited matrix metalloproteinase-1 (MMP-1) production most effectively. Phytochemical study on the EtOAC fraction resulted in the isolation of three compounds; eutigoside C (1), eutigoside B (2) and quercitrin (3). Among the isolates (1-3), quercitrin (3) showed excellent antioxidant activities and inhibitory properties on MMP-1 production. Based on these results, it was suggested that extracts of E. emarginata leaves could be developed as natural anti-photoaging agents in cosmetic formulations.
ISSN:1017-2548
2234-8530
DOI:10.5012/jkcs.2023.67.2.150