Exploration of errors in variance caused by using the first-order approximation in Mendelian randomization

Mendelian randomization (MR) uses genetic variation as a natural experiment to investigate the causal effects of modifiable risk factors (exposures) on outcomes. Two-sample Mendelian randomization (2SMR) is widely used to measure causal effects between exposures and outcomes via genome-wide associat...

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Veröffentlicht in:Genomics & informatics 2022, Vol.20 (1), p.9.1-9.6
Hauptverfasser: Kim, Hakin, Kim, Kunhee, Han, Buhm
Format: Artikel
Sprache:kor
Online-Zugang:Volltext
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