Two New Flavanones from the Leaves of Flemingia lineata (L.) Aiton

Two New Flavanones from the Leaves of Flemingia lineata (L.) Aiton

Three isoprenylated flavanones were isolated from the leaves of Flemingia lineata (L.) Aiton. Among them are two new flavanones, flemilineatins A and B (1-2), along with 6-isoprenyl eridioctyol (3). Their structures were determined using HRESIMS data and NMR spectra. Flavanones 1-3 were assayed in t...

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Veröffentlicht in:Natural product sciences 2022, Vol.28 (1), p.40-43
Hauptverfasser: Tanjung, Mulyadi, Tjahjandarie, Tjitjik Srie, Mardhiyyah, Shola, Rahman, Ghinsha Zakatina, Aldin, Muhammad Fajar, Saputri, Ratih Dewi, Ahmat, Norizan
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Zusammenfassung:Three isoprenylated flavanones were isolated from the leaves of Flemingia lineata (L.) Aiton. Among them are two new flavanones, flemilineatins A and B (1-2), along with 6-isoprenyl eridioctyol (3). Their structures were determined using HRESIMS data and NMR spectra. Flavanones 1-3 were assayed in the HeLa cancer cells. Compound 1 showed moderate activity with an IC50 value of 11.2 μM.
ISSN:1226-3907