Anti-oxidative effects of Phellinus Linteus and red ginseng extracts on oxidative stress-induced DNA damage

Anti-oxidative effect of Phellinus linteus (P. linteus) and red ginseng extracts on DNA damage induced by reactive oxygen species (ROS) were investigated in this study. P. linteus (PLE) and red ginseng extracts (RGE) inhibited the breaking of E. coli ColE1 plasmid DNA strands as well as nuclear DNA...

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Veröffentlicht in:BMB reports 2009-08, Vol.42 (8), p.500-505
Hauptverfasser: Park, Byung-Jae, Lim, Yeong-Seok, Lee, Hee-Jung, Eum, Won-Sik, Park, Jin-Seu, Han, Kyu-Hyung, Choi, Soo-Young, Lee, Kil-Soo
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container_issue 8
container_start_page 500
container_title BMB reports
container_volume 42
creator Park, Byung-Jae
Lim, Yeong-Seok
Lee, Hee-Jung
Eum, Won-Sik
Park, Jin-Seu
Han, Kyu-Hyung
Choi, Soo-Young
Lee, Kil-Soo
description Anti-oxidative effect of Phellinus linteus (P. linteus) and red ginseng extracts on DNA damage induced by reactive oxygen species (ROS) were investigated in this study. P. linteus (PLE) and red ginseng extracts (RGE) inhibited the breaking of E. coli ColE1 plasmid DNA strands as well as nuclear DNA of rat hepatocytes damaged by oxidative stress. In addition, a reaction mixture of PLE and RGE showed synergistic inhibitory effect against DNA damage. These results suggest that PLE and RGE have a cellular defensive effect against DNA damage induced by ROS.
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identifier ISSN: 1976-6696
ispartof BMB reports, 2009-08, Vol.42 (8), p.500-505
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1976-670X
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source DOAJ Directory of Open Access Journals; Free Full-Text Journals in Chemistry
subjects Antioxidant
DNA damage
P. Linteus
Phellinus Linteus
Reactive oxygen species
Red ginseng
ROS
title Anti-oxidative effects of Phellinus Linteus and red ginseng extracts on oxidative stress-induced DNA damage
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