Anti-oxidative effects of Phellinus Linteus and red ginseng extracts on oxidative stress-induced DNA damage
Anti-oxidative effect of Phellinus linteus (P. linteus) and red ginseng extracts on DNA damage induced by reactive oxygen species (ROS) were investigated in this study. P. linteus (PLE) and red ginseng extracts (RGE) inhibited the breaking of E. coli ColE1 plasmid DNA strands as well as nuclear DNA...
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Veröffentlicht in: | BMB reports 2009-08, Vol.42 (8), p.500-505 |
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description | Anti-oxidative effect of Phellinus linteus (P. linteus) and red ginseng extracts on DNA damage induced by reactive oxygen species (ROS) were investigated in this study. P. linteus (PLE) and red ginseng extracts (RGE) inhibited the breaking of E. coli ColE1 plasmid DNA strands as well as nuclear DNA of rat hepatocytes damaged by oxidative stress. In addition, a reaction mixture of PLE and RGE showed synergistic inhibitory effect against DNA damage. These results suggest that PLE and RGE have a cellular defensive effect against DNA damage induced by ROS. |
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P. linteus (PLE) and red ginseng extracts (RGE) inhibited the breaking of E. coli ColE1 plasmid DNA strands as well as nuclear DNA of rat hepatocytes damaged by oxidative stress. In addition, a reaction mixture of PLE and RGE showed synergistic inhibitory effect against DNA damage. These results suggest that PLE and RGE have a cellular defensive effect against DNA damage induced by ROS.</description><identifier>ISSN: 1976-6696</identifier><identifier>EISSN: 1976-670X</identifier><language>kor</language><publisher>생화학분자생물학회</publisher><subject>Antioxidant ; DNA damage ; P. 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P. linteus (PLE) and red ginseng extracts (RGE) inhibited the breaking of E. coli ColE1 plasmid DNA strands as well as nuclear DNA of rat hepatocytes damaged by oxidative stress. In addition, a reaction mixture of PLE and RGE showed synergistic inhibitory effect against DNA damage. These results suggest that PLE and RGE have a cellular defensive effect against DNA damage induced by ROS.</description><subject>Antioxidant</subject><subject>DNA damage</subject><subject>P. Linteus</subject><subject>Phellinus Linteus</subject><subject>Reactive oxygen species</subject><subject>Red ginseng</subject><subject>ROS</subject><issn>1976-6696</issn><issn>1976-670X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>JDI</sourceid><recordid>eNpFjMtqwzAUREVpoSHNF3SjTZcGyZIsa2nSZxqaLrLozsjSlSvsKMVSSvr3FX3CwAzM4ZygGVWyKipJXk5_d6Wqc7SI0XeEc8moVGSGhiYkX-yP3urk3wGDc2BSxHuHn19hHH04RLz2IUFuHSyewOLehwihx3BMk_6iA_5XxDRBjIUP9mAyfP3UYKt3uocLdOb0GGHx03O0vb3ZLu-L9ebuYdmsi0EQUQhDNHU156TmmlSMG00lUMXAVI6xznbCGi4UdcxwpVkpVQfCKsbLfBnC5ujqWzv4mHwbbBzbVfO4KQlRlFDCeC1yMnf5x8X2bfI7PX20WcelrNknMmlekQ</recordid><startdate>20090831</startdate><enddate>20090831</enddate><creator>Park, Byung-Jae</creator><creator>Lim, Yeong-Seok</creator><creator>Lee, Hee-Jung</creator><creator>Eum, Won-Sik</creator><creator>Park, Jin-Seu</creator><creator>Han, Kyu-Hyung</creator><creator>Choi, Soo-Young</creator><creator>Lee, Kil-Soo</creator><general>생화학분자생물학회</general><scope>HZB</scope><scope>Q5X</scope><scope>JDI</scope></search><sort><creationdate>20090831</creationdate><title>Anti-oxidative effects of Phellinus Linteus and red ginseng extracts on oxidative stress-induced DNA damage</title><author>Park, Byung-Jae ; Lim, Yeong-Seok ; Lee, Hee-Jung ; Eum, Won-Sik ; Park, Jin-Seu ; Han, Kyu-Hyung ; Choi, Soo-Young ; Lee, Kil-Soo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-k505-5c0a1f844084a0634ca17e193ec6f33bdb5dc4591f3c49a3279be5d9342db5c03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>kor</language><creationdate>2009</creationdate><topic>Antioxidant</topic><topic>DNA damage</topic><topic>P. Linteus</topic><topic>Phellinus Linteus</topic><topic>Reactive oxygen species</topic><topic>Red ginseng</topic><topic>ROS</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Park, Byung-Jae</creatorcontrib><creatorcontrib>Lim, Yeong-Seok</creatorcontrib><creatorcontrib>Lee, Hee-Jung</creatorcontrib><creatorcontrib>Eum, Won-Sik</creatorcontrib><creatorcontrib>Park, Jin-Seu</creatorcontrib><creatorcontrib>Han, Kyu-Hyung</creatorcontrib><creatorcontrib>Choi, Soo-Young</creatorcontrib><creatorcontrib>Lee, Kil-Soo</creatorcontrib><collection>Korean Studies Information Service System (KISS)</collection><collection>Korean Studies Information Service System (KISS) B-Type</collection><collection>KoreaScience</collection><jtitle>BMB reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Park, Byung-Jae</au><au>Lim, Yeong-Seok</au><au>Lee, Hee-Jung</au><au>Eum, Won-Sik</au><au>Park, Jin-Seu</au><au>Han, Kyu-Hyung</au><au>Choi, Soo-Young</au><au>Lee, Kil-Soo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Anti-oxidative effects of Phellinus Linteus and red ginseng extracts on oxidative stress-induced DNA damage</atitle><jtitle>BMB reports</jtitle><addtitle>BMB Reports</addtitle><date>2009-08-31</date><risdate>2009</risdate><volume>42</volume><issue>8</issue><spage>500</spage><epage>505</epage><pages>500-505</pages><issn>1976-6696</issn><eissn>1976-670X</eissn><abstract>Anti-oxidative effect of Phellinus linteus (P. linteus) and red ginseng extracts on DNA damage induced by reactive oxygen species (ROS) were investigated in this study. P. linteus (PLE) and red ginseng extracts (RGE) inhibited the breaking of E. coli ColE1 plasmid DNA strands as well as nuclear DNA of rat hepatocytes damaged by oxidative stress. In addition, a reaction mixture of PLE and RGE showed synergistic inhibitory effect against DNA damage. These results suggest that PLE and RGE have a cellular defensive effect against DNA damage induced by ROS.</abstract><pub>생화학분자생물학회</pub><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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identifier | ISSN: 1976-6696 |
ispartof | BMB reports, 2009-08, Vol.42 (8), p.500-505 |
issn | 1976-6696 1976-670X |
language | kor |
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source | DOAJ Directory of Open Access Journals; Free Full-Text Journals in Chemistry |
subjects | Antioxidant DNA damage P. Linteus Phellinus Linteus Reactive oxygen species Red ginseng ROS |
title | Anti-oxidative effects of Phellinus Linteus and red ginseng extracts on oxidative stress-induced DNA damage |
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