Anti-oxidative effects of Phellinus Linteus and red ginseng extracts on oxidative stress-induced DNA damage

Anti-oxidative effects of Phellinus Linteus and red ginseng extracts on oxidative stress-induced DNA damage

Anti-oxidative effect of Phellinus linteus (P. linteus) and red ginseng extracts on DNA damage induced by reactive oxygen species (ROS) were investigated in this study. P. linteus (PLE) and red ginseng extracts (RGE) inhibited the breaking of E. coli ColE1 plasmid DNA strands as well as nuclear DNA...

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Veröffentlicht in:BMB reports 2009-08, Vol.42 (8), p.500-505
Hauptverfasser: Park, Byung-Jae, Lim, Yeong-Seok, Lee, Hee-Jung, Eum, Won-Sik, Park, Jin-Seu, Han, Kyu-Hyung, Choi, Soo-Young, Lee, Kil-Soo
Format: Artikel
Sprache:kor
Schlagworte:
Antioxidant
DNA damage
P. Linteus
Phellinus Linteus
Reactive oxygen species
Red ginseng
ROS
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Zusammenfassung:Anti-oxidative effect of Phellinus linteus (P. linteus) and red ginseng extracts on DNA damage induced by reactive oxygen species (ROS) were investigated in this study. P. linteus (PLE) and red ginseng extracts (RGE) inhibited the breaking of E. coli ColE1 plasmid DNA strands as well as nuclear DNA of rat hepatocytes damaged by oxidative stress. In addition, a reaction mixture of PLE and RGE showed synergistic inhibitory effect against DNA damage. These results suggest that PLE and RGE have a cellular defensive effect against DNA damage induced by ROS.
ISSN:1976-6696
1976-670X