Stereoselective Synthesis of (E)-and (Z)-Enol Ethers from ${\beta}$-Amino Aldehydes

Stereocontrolled methods for the direct and divergent synthesis of the silylenol ethers possessing amino group from ${\beta}$-amino aldehydes have been achieved. These enol ethers with the defined olefin geometry could be key building blocks for the synthesis of the medicinally important compounds.

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Veröffentlicht in:Archives of pharmacal research 2007, Vol.30 (6), p.695-700
Hauptverfasser: In, Jin-Kyung, Lee, Mi-Sung, Lee, Min-Woo, Kwak, Jae-Hwan, Lee, Hee-Soon, Hong, Jin-Tae, Chung, Yong-Seog, Choi, Yong-Seok, Jung, Jae-Kyung
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Sprache:kor
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Zusammenfassung:Stereocontrolled methods for the direct and divergent synthesis of the silylenol ethers possessing amino group from ${\beta}$-amino aldehydes have been achieved. These enol ethers with the defined olefin geometry could be key building blocks for the synthesis of the medicinally important compounds.
ISSN:0253-6269
1976-3786