Fermentation Strategies for Recombinant Protein Expression in the Methylotrophic Yeast Pichia pastoris
Fermentation strategies for recombinant protein production in Pichia pastoris have been investigated and are reviewed here. Characteristics of the expression system, such as phenotypes and carbon utilization, are summarized. Recently reported results such as growth model establishment, app58lication...
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| Veröffentlicht in: | Biotechnology and bioprocess engineering 2000, Vol.5 (4), p.275-287 |
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| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | kor |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | Fermentation strategies for recombinant protein production in Pichia pastoris have been investigated and are reviewed here. Characteristics of the expression system, such as phenotypes and carbon utilization, are summarized. Recently reported results such as growth model establishment, app58lication of a methanol sensor, optimization of substrate feeding strategy, DOstat controller design, mixed feed technology, and perfusion and continuous culture are discussed in detail. |
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| ISSN: | 1226-8372 1976-3816 |