석창포(石菖蒲) 전탕액(煎湯液)이 Glucose Oxidase에 의해 손상(損傷)된 대뇌피질(大腦皮質) 신경세포(神經細胞)에 미치는 영향(影響)

The purpose of this study is to examine the toxic effects caused by Glucose Oxidase(GO) and the effects of herbal extracts such as Acori Rhizoma(AR) on the treatment of the toxic effects. For this purpose, experiments with the cultured cell from the cerebrums of new born mice were done. The results...

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Veröffentlicht in:동의생리학회지 1999, Vol.14 (2), p.117-126
Hauptverfasser: 최공한, 박승택, 류도곤, 최민호, 허진영, 강성도, 고정수, 양상철, 성은경, 조남수, 이춘우, 서의석, 류영수, Choi, Kong-Han, Park, Seung-Taeck, Ryu, Do-Gon, Choi, Min-Ho, Hea, Jin-Young, Kang, Sung-Do, Go, Jeong-Soo, Yang, Sang-cheal, Sung, Yeun-Kyung, Cho, Nam-Su, Lee, Chun-Woo, Sou, Eui-Suk, Ryu, Young-Su
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Sprache:kor
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Zusammenfassung:The purpose of this study is to examine the toxic effects caused by Glucose Oxidase(GO) and the effects of herbal extracts such as Acori Rhizoma(AR) on the treatment of the toxic effects. For this purpose, experiments with the cultured cell from the cerebrums of new born mice were done. The results of these experiments were as follows. 1. GO, a oxygen radical, decreased the survival rate of the cultured cells on NR assay and MTT assay. 2. GO, a oxygen radical, decreased the amount of neurofilaments and total protein. 3. AR have efficacy of increasing the amount of neurofilament. 4. AR have efficacy of increasing the amount of total protein. From the above results, It is concluded that AR has marked efficacy as a treatment for the damages caused in the GO-mediated oxidative process. And AR is thought to have certain pharmacological effects on controlling over aging. Further clinical study of this pharmacological effects of AR should be complemented.
ISSN:1010-0695