한국산 해양 의충동물 개불에서 Anthraquinone 및 Sterol 성분연구

Three anthraquinones, chrysophanol, physcion and 1-o-methyl-2-methoxychrysophanol which have $Na^+,K^+-ATPase$ and cyclic AMP phosphodiesterase lowering activities related to cardiotonic action were isolated from the Korean marine echiura, Urechis unicintus. Spectroscopic methods, including HMQC, HM...

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Veröffentlicht in:	Journal of the Korean Chemical Society 1998, Vol.42 (1), p.64-68
Hauptverfasser:	채석(Seuk Chai), 김인규(In Kyu Kim), 서영완(Young Wan Seo), 조기웅(Ki Woong Cho), 신종헌(Jong Heon Shim), 장성근(Sung Keun Chang), 박영현(Yong Hyun Park)
Format:	Artikel
Sprache:	kor
Online-Zugang:	Volltext
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Zusammenfassung:	Three anthraquinones, chrysophanol, physcion and 1-o-methyl-2-methoxychrysophanol which have $Na^+,K^+-ATPase$ and cyclic AMP phosphodiesterase lowering activities related to cardiotonic action were isolated from the Korean marine echiura, Urechis unicintus. Spectroscopic methods, including HMQC, HMBC and NOE studies, were used to establish the structures. 한국 연해에 서식하고 있는 의충동물 개불(Urechis unicintus)로 부터 강심작용과 관련된 $Na^+,K^+-ATPase$ 저해 작용 및 cyclic AMP phosphodiesterase 저해 작용이 높은 anthraquinones화합물인 chrysophanol, physcion 및 1-o-methyl-2methoxychrysophanol을 분리하였다.주로 HMQC, HMBC 및 NOE 등의 분광학적 방법으로 이들의 구조를 밝혔다.
ISSN:	1017-2548 2234-8530